What is Obesity?

What is Obesity?

Obesity is a state of excessive accumulation of adipose tissue.
BMI is used to determine obesity.

A BMI of 22 kg/m2, which has the lowest rate of disease complications, is considered the standard weight.

A BMI ≥ 25 kg/m2 is considered obese.

Obesity causes not only metabolic diseases such as diabetes and dyslipidemia, and coronary artery disease and cerebrovascular disease, but also various health problems such as sleep apnea, renal disorders, bone and joint diseases, and menstrual disorders.

Health problems caused by obesity

・Impaired glucose tolerance (diabetic and borderline)
・Hyperuricemia and gout
・Coronary artery disease (angina pectoris, myocardial infarction)
・Cerebral infarction
・Fatty liver
・Menstrual abnormalities/infertility
・Sleep apnea syndrome, obesity hypoventilation syndrome
・Musculoskeletal disease
・Obesity-related kidney disease
・The following 11 diseases are listed.

In addition, although not included in the diagnostic criteria, the following diseases are associated with obesity and should be noted: cholelithiasis, venous thromboembolism/pulmonary embolism, bronchial asthma, skin diseases, male infertility, gastroesophageal reflux disease, and a series of malignant diseases (colon cancer, esophageal cancer, uterine cancer, pancreatic cancer, kidney cancer, breast cancer, etc.).

Sleep-disordered breathing

Among sleep-disordered breathing disorders, obstructive sleep apnea syndrome (OSAS) is closely related to obesity.

The subjective symptoms of OSAS include breathlessness during sleep, daytime sleepiness, and headache upon awakening, but it is usually detected by others through optimal snoring and cessation of breathing during sleep.

OSAS causes hypoxemia and has been linked to cardiovascular events such as hypertension, angina pectoris, myocardial infarction, and stroke.

Heart failure

Severe obesity can lead to heart failure.

The subjective symptoms of heart failure include generalized edema, pulmonary congestion, and dyspnea.

It is known that obstructive sleep apnea is one of the causes of heart failure, which puts a strain on the heart and causes a gradual decline in heart function.

Obesity-related kidney disease

Severe obesity is known to cause inflammation of the kidneys.

In the early stages, proteinuria can be detected on urinalysis, which improves with weight loss, but if left untreated, it can progress to renal failure.

Musculoskeletal disorder

Severe obesity is also an exacerbating factor for osteoarthritis.

Particularly impacting life are hip and knee arthritis, both of which cause deformities in joint cartilage and bone due to muscle weakness, aging, and obesity.

Benefits of Losing Weight

Many overweight people want to lose weight to look better.

However, there are also medical reasons why being overweight should be improved. Heart disease, stroke, type II diabetes, high blood pressure, and certain types of cancer have been linked to being overweight.

If you are already overweight, you need to lose weight systematically. It is recommended that you consult your physician before starting any new fitness program.

Obesity Treatment Goals

The goal of obesity treatment is to eliminate or reduce or prevent the health problems associated with obesity through weight loss.

The first goal is to lose 3% of your current weight in 3-6 months.

It has been proven that a 3-5% weight loss improves triglycerides, HDL-C, LDL-C, HbA1c, liver function, systolic and diastolic blood pressure.

Continued weight loss without rebound is the most effective way to improve complications.

Feature of Holiday-Pill

✓ Weight concern and staying in Japan?
✓ Delivery to all over Japan, Automatic refill.
✓ Easy application via chat in English
✓ Arrive next day at fastest
✓ First Month: 4,000 yen (Less than $30, Including Shipping)

Quick Service saves your time

Simple and smooth Online service through in English.
Skilled staff and doctors provide speedy service.

Real reviews from users

To apply for prescription, contact us on our LINE below button.

Clinic schedule

【Open Hours】
◆ Mon〜Thu: 7:00 – 16:00
(Break time: 14:00 – 15:00)
Last reception time for online:15:30 – 16:00
Last reception time for visit:15:45

◆ Sun, Holiday : 9:00 – 21:00
(Break time: 14:00 – 15:00)
Last reception time for online: 20:30 – 21:00
Last reception time for visit: 20:45

ーWe are regularly closed on Fri, Sat.

Flow of our clinic

1. Apply from LINE

Apply from LINE.

Please fill out the web medical questionnaire.

Available 24 hours.

2. Phone Consultation

Medical examination by the phone.

If you have any concerns, please ask our doctor at that time.

3. Recieve the Pills by direct pick-up or delivery.

Two ways to get your medicine are available. You can choose to pick up in-person or wait at home for delivery.

In delivery case, we can same-day shipping. Check with our counselors for delivery schedule.

In pick up case, recieve pills at the clinic, a 5-minute walk from Akihabara and Kanda stations.

Post Area

Basically, we can delivery to your door.

Next-day delivery is available to most areas in Japan. Please check also the map.

↓Click here for consultation and application↓

Frequently asked questions

Q.Are there any side effects of taking the the medical diet medicine?
A.The following initial symptoms may occur Lactic acidosis, liver dysfunction, hypoglycemia, rhabdomyolysis. If any of these symptoms are observed, stop taking the drug and consult a physician.

Q. Do I need an insurance card? Will there be a record of its use?
A.As the treatment is self-funded, there is no need to present it.

Q.Is there a specified delivery area?
A. Basically, we can deliver throughout Japan (delivery from Tokyo).

Q.When and how do I make payment?
A.Payment can be easily made on LINE/WhatsApp account.
 Payment will be made by credit card.

How can we help you?

Director / Physician
Yuki Kakehashi


Graduated from Tokyo Jikei University School of Medicine in 2014
2014 Worked at Yokohama City Municipal Hospital
August 2021 Appointed Director of Takeshi Internal Medicine Akihabara Kanda 

・Member of the Japanese Society of Anti-Aging Medicine
・Member of the Japanese Society of Clinical Hair Growth
・Certified mammography reader by the Japan Central Organization on Quality Assurance of Breast Cencer Screening
・Japan Medical Association Certified Industrial Physician

Take Clinic Akihabara Kanda
TEL: 03-5296-8181
Tokyo, Chiyoda-ku KandaSudacho2-6-10 2F
Director Doctor: Yuki Kakehashi

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